AACR 2025 was an incredible experience — Packed with innovation, collaboration, and scientific breakthroughs of how spatial biology and multi-omics are shaping the future of cancer research.
Key Highlights from AACR 2025
- 2-Fold Sensitivity Advancement with CosMx® 2.0
- Advance Ordering for the CosMx® Whole Transcriptome Assay
- nCounter® Platform to Offer Multiomic Assays
- GeoMx® to Offer Highest Plex Spatial Multiomics with 1200+ proteins
- Unlocking 3D Genome Structure with the PaintScape™ Platform
- CellScape™ Platform with New Software Engine to Improve Throughput and Data Quality
We appreciate everyone who stopped by our booth, poster sessions, and attended our Spotlight Theater presentation. Thank you for being a part of this exciting journey in spatial biology and see you next year in Sunny San Diego!
Download the posters from the event by filling out the form below.
Posters
| 2779 | Functional Genomics: Large Scale Approaches to Cancer Gene Discovery | April 28 2pm-5pm | 11 | Whole transcriptome spatial CRISPR screening of tumor cells and spheroids with nanometer resolution: Y. Cui | Merck & Co, Inc, Bruker Spatial Biology | CosMx |
| 2080 | Spatial Proteomics and Transcriptomics 2 | April 28 9am-12pm | 32 | Whole Transcriptome Single Cell Spatial Imaging of Tumor vs Normal Tissue Microarray: J. Beechem | Bruker Spatial Biology | CosMx |
| 2067 | Spatial Proteomics and Transcriptomics 2 | April 28 9am-12pm | 32 | Single-cell spatial whole transcriptome reveals tumor heterogeneity and stromal dynamics in invasive ductal carcinoma of the breast: L. Zhang | Bruker Spatial Biology | CosMx |
| 2078 | Spatial Proteomics and Transcriptomics 2 | April 28 9am-12pm | 32 | Single-cell spatial transcriptomics in colon adenocarcinoma reveals tumor heterogeneity and immune microenvironmental shifts: M. Hoang | Bruker Spatial Biology | CosMx |
| 2068 | Spatial Proteomics and Transcriptomics 2 | April 28 9am-12pm | 32 | Mapping the spatial whole transcriptome from normal to tumor tissue in renal clear cell carcinoma: Tumorigenesis and microenvironmental shifts at single-cell resolution: S. He | Bruker Spatial Biology | CosMx |
| 2091 | Spatial Proteomics and Transcriptomics 2 | April 28 9am-12pm | 32 | Integrating single-cell spatial whole transcriptome and histopathology to uncover drivers of tumor heterogeneity in lung adenocarcinoma and squamous cell carcinoma: M. Patrick | Bruker Spatial Biology | CosMx |
| 751 | Spatial Proteomics and Transcriptomics 1 | April 27 2pm-5pm | 32 | High-resolution and AI-enabled single-cell spatial transcriptomics and histopathology integrated to reveal tumor differentiation and immune exclusion in skin squamous cell carcinoma: P. Danaher | Bruker Spatial Biology | CosMx |
| 1880 | Proteomic Signatures in Cancer | April 28 9am-12pm | 26 | Advancing spatial discovery multiomics: Integration of a novel 1000+ plex discovery proteome atlas with an 18,000+ plex whole transcriptome atlas for same-slide investigation multiple cancer pathologies: A. Heck | Bruker Spatial Biology | GeoMx |
| 177 | Where's Waldo: Spatial Complexity of the Tumor Microenvironment 1 | April 27 2pm-5pm | 7 | Increasing throughput of high-quality spatial biology data via low magnification, high NA scanning on the CellScape platform: J.Schwarz | Bruker Spatial Biology | CellScape |
| 2084 | Spatial Proteomics and Transcriptomics 2 | April 28 9am-12pm | 32 | Development of a novel tri-omic spatial biology assay that provides in-depth immune profiling of the tumor immune microenvironment: A. Christians | Bruker Spatial Biology | CellScape |
| 6483 | Multi-omics and the Predictive Power of the Tumor Microenvironment | April 30 9am-12pm | 2 | Powerful end-to-end spatial analyses using precise spatial proteomics: C. Jackson | Bruker Spatial Biology | CellScape |
| 7106 | Revolutionizing Cancer Care Through Inclusive Clinical Research | April 30 9am-12pm | 30 | Comprehensive spatial profiling of the tumor immune microenvironment in triple negative breast cancer from Black women: F. Dezem, A. Christians, O. Braubach, J. Plummer | St. Jude Children's Research Hospital, Bruker Spatial Biology | CellScape |
| 2746 | Epigenetic Mechanisms of Cancer Resistance and Progression | April 28 2pm-5pm | 10 | 3D genome structural alterations in biological pathway genes drive the progression of cells from normal epithelium to metastatic cancer: H. Nguyen | Bruker Spatial Biology | PaintScape |
| 2852 | Origins and Mechanisms of Genomic Instability | April 28 2pm-5pm | 14 | Mapping single cell spatial 3D genome landscape of localized and metastatic breast cancer sub-types: J. Dunne | Bruker Spatial Biology | PaintScape |
| 5073 | Single Cell and Spatial Molecular Analysis | April 29 9am-12pm | 47 | Whole transcriptome spatial molecular imaging in matched pre and post treatment specimens to identify treatment-associated effects in pancreatic adenocarcinoma: B. Aswathi | Massachusetts General Hospital | CosMx |
| 6466 | Multi-omics and the Predictive Power of the Tumor Microenvironment | April 30 9am-12pm | 2 | Discovery Proteome and Whole Transcriptome Atlas analysis of skin cancer reveals biomarkers associated with immunotherapy response and resistance: A. Kulasinghe | Frazer Institute, The University of Queensland | GeoMx |
| 1372 | Uncovering How Secreted Factors Sculpt the Tumor Microenvironment | April 28 9am-12pm | 7 | Development of a multi-omic spatial phenotyping assay for affirmative detection of CAR-T cells in the tumor immune microenvironment of solid pediatric tumors J.Plummer, F. Segato-Dezem, Y. Liu, A. Wani, H. Chasteen, A. Christians, J. Boog, R. Chen, H. Choi, A. Acharya, O. Braubach, G. Krenciute, J. Chiang, C. De Renzo, K. Bertrand | St. Jude Children's Research Hospital, Bruker Spatial Biology | CellScape |