Optimizing Multiplex Immunofluorescence Assays on the CellScape Platform
Over the last few years, more and more researchers have embraced multiplex immunofluorescence (mIF), and for good reason. The ability to visualize many biomarkers in a single tissue section can transform a standard immunostaining experiment into a deep dive on cellular neighborhoods, signaling pathways, and immune infiltration. The CellScape™ Precise Spatial Proteomics platform is a…
Read MoreIntroducing Enhanced Photobleaching in Cyclic Immunofluorescence for Spatial Biology
FFPE tonsil, captured on the CellScape Platform with EpicIF Technology. Bruker Spatial Biology is pleased to introduce EpicIF™ signal removal technology for the CellScape™ Precise Spatial Proteomics platform. EpicIF technology empowers high-plex cycling and maximum flexibility in target selection by erasing photostable fluorophores. The gentle method quickly removes fluorescence signals while preserving tissue integrity through…
Read MoreData-driven Assay Expansion: Re-examine Multiplex Immunofluorescence Slides Based on Initial Staining Results
Imagine this: you’ve just completed your multiplex immunofluorescence experiment, and when examining your images, you notice something intriguing or novel about the tissue or a certain subset of cells. In practice, you’d expand the panel to include additional biomarkers and run another experiment; however, the thought of repeating the sample collection, sectioning tissues, and preparing…
Read MoreSpatial Biology Just Got Bigger
Introducing CellScape™ Whole-Slide Imaging Chamber Now you can convert any standard microscope slide into a microfluidic chamber for automated multiplex staining, high-resolution imaging, and safe sample archiving. Read more about the expansion of our Precise Spatial Multiplexing capabilities. Whole-slide spatial biology Spatial biology is a rapidly growing field that enables exploration and visualization of tissues…
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