Providing Novel Insights for Cancer Research
Explore the tumor microenvironment with highly resolved multiplex immunofluorescence imaging. See how CellScape Precise Spatial Proteomics (formerly called ChipCytometry technology) has been utilized to probe cancer biology and monitor treatment progress.
Unraveling Relationships Between Microbiome, Immunity, and Carcinogenesis
In this publication by Dr. Anna Ralser and the Gerhard Lab, Precise Spatial Proteomics provided important context to one of the most common drivers of gastric and colorectal carcinogenesis by demonstrating the mechanism of Helicobacter pylori infection-driven carcinogenesis.
This study serves as a powerful example of how spatial biology can be applied in translational research to explore hypotheses and unveil novel mechanisms leading to the emergence and progression of cancer.
Monitoring Efficacy of Microbeam Radiation Therapy
Verdiana Trappetti and colleagues of the University of Bern explored the efficacy of microbeam radiation therapy for radioresistant melanoma and metastases in mice.
Supported by Precise Spatial Proteomics to identify immune cell lineages from irradiated tumors, they identified a treatment protocol of double microbeam radiation therapy that inhibited melanoma progression and reduced metastasis. Spatial immunophenotyping facilitated the evaluation of therapeutic efficacy and monitored treatment progression – a key step toward personalized medicine.
CellScape Precise Spatial Proteomics
The CellScape platform offers the most versatile spatial biology solution – compatible with both off-the-shelf antibodies and our expandable VistaPlex™ Assay Kits.
Combining best-in-class image acquisition with easy-to-use fluidics for walk-away automation, CellScape accelerates biological discovery and therapeutic development.
Accelerate Your Oncology Insights
Supported by curated panels for robust gene expression analysis, the nCounter® Analysis Platform provides a cost-effective solution for multiplex analysis of up to 800 biomarker targets.
Discover and evaluate disease and prognosis indicators or monitor treatment progress with high sensitivity and accuracy.