CellScape™ Precise Spatial Proteomics Services

NEW: Enhanced Photobleaching in Cyclic Immunofluorescence (EpicIF)

Remove fluorescence signal from any organic dye for highly multiplexed immunofluorescence.

Access Cutting-Edge Spatial Phenotyping Capabilities

The most flexible platform in the industry, CellScape is compatible with both suspension cells and intact tissue samples, allowing for more comprehensive experiments. Investigate liquid and solid tumor biopsies from the same source with our single system.

Partner with us to efficiently incorporate spatial biology into your next biomarker discovery project or clinical trial.

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Made by Experts, Run by Experts

Unlike other spatial phenotyping service providers, we don’t only offer platforms, we create them. Experience the power of working with leaders in the field.

Spatial Data Your Way

Spatial phenotyping reveals deeper biological insights in your tissue. Our scientists can help you unravel these insights with standard and custom acquisition and analysis options.

Get Started Right Now

Accelerate your time to spatial biology access by utilizing our labs – no instrument required. Send your samples and let us do the work.

Full Spatial Suite

We offer a unique, curated mix of spatial and single-cell technologies to complement CellScape spatial phenotyping for end-to-end coverage.

Protein-Protein Interactions in situ

How Our CellScape Service Works

We execute our CellScape Service workflow in four simple steps, seamlessly taking you from spatial biomarker selection to robust spatial phenotyping data.

Choose

Design Your Panel

Use your preferred antibodies or our CellScape Multiplexing Panels. We can detect both standard and unique biomarkers using our high-plex spatial assays.

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Send Your Samples

The CellScape platform is compatible with a range of sample types, including PBMCs, CSF, FF and FFPE tissue, and TMAs. Use your samples or leverage our high-quality biobanks.

Scientist

We Do the Work

We offer an end-to-end service, including sample preparation, Precise Spatial Proteomics on our instrumentation, and data export.

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You Get Your Data

Select our standard offering or customize your analysis to fit your project needs. We create final outputs catered to how involved, or uninvolved, you want to be with your analysis.

How We Leverage the CellScape Workflow

Our streamlined CellScape platform provides high-throughput microscopy with single-cell resolution, enabling the most accurate spatial phenotyping. Reclaim your time without compromising on data quality.

CellScape Precise Spatial Multiplexing workflow- the platform cycles through immunostaining, imaging, and signal removal to enable multiple rounds of fluorescence imaging.
Speed

After preparation of suspension cell or tissue samples, CellScape integrated fluidics enables walkaway automation of staining and imaging, facilitating short experiment times and rapid data delivery.

Precision

CellScape offers best-in-class digital sampling at 182 nm/pixel combined with market-leading dynamic range to detect protein expression across 8 orders of magnitude. See what you’ve been missing.

Flexibility

With versatile reagent selection, you can add research-specific context into a robust immune environment. Customize our highly tested CellScape Multiplexing Panels with your own favorite fluorescently labeled markers.

Get Data Faster with CellScape Multiplexing Panels

CellScape Multiplexing Panels are designed to provide coverage of key tumor and immune cell biomarkers for immuno-oncology research applications. Panels are all expandable by combining with other panels or adding unique biomarkers.

The Broad Immune Profiling Panel enables quantification of 16 phenotypic biomarkers that define T Cell, B Cell, Leukocyte, NK Cell, NKT Cell, Monocyte, Dendritic and Exhaustion Cell populations and sub-populations in human PBMC samples

The Rapid Immune Profiling Panel enables quantification of 10 phenotypic biomarkers that define T Cell, B Cell, Leukocytes, NK Cell, NKT Cell, Monocyte and Dendritic Cell populations and sub-populations in human PBMC samples

The T-Cell Panel enables quantification of 8 phenotypic biomarkers that define T-cell populations and subpopulations in human PBMC samples

The Lymphoid and Myeloid Profiling Panel enables quantification of 12 phenotypic biomarkers that define T Cell, B Cell, Leukocyte, NK Cell, NKT Cell and Monocyte Cell populations and sub-populations in human PBMC samples

The Spatial Immune Profiling Panel enables quantification of 14 phenotypic biomarkers that define T Cell, B Cell, Leukocyte, NK Cell, NKT Cell, Monocyte, Dendritic and Epithelial Cell populations and sub-populations in human FF samples

The Spatial Immune Profiling Panel enables quantification of 13 phenotypic biomarkers that define T Cell, Macrophage, Exhaustion and Epithelial Cell populations and sub-populations in human FFPE samples.

Dr. Sarah Harris

Head, GI. & Neurology, Atopic Disorder Disease Teams, Translational Medicine, BMS

“CellScape Services allowed us to utilize small amounts of stored clinical samples to investigate tissue architecture and localization of a large number of cell types in multiple diseases, as well as how treatment altered those characteristics.”

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Expand Your Experiment

After your CellScape project, utilize our full suite of cutting-edge spatial, histopathological, and gene expression services to expand your study and corroborate your CellScape spatial multiplexing insights.

Ready for Your Own CellScape?

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Featured Resources

Publication

Phase II trial of nivolumab and metformin in patients with treatment-refractory microsatellite stable metastatic colorectal cancer

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Publication

T cell-derived interleukin-22 drives the expression of CD155 by cancer cells to suppress NK cell function and promote metastasis

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Publication

Bispecific antibodies redirect synthetic agonistic receptor modified T cells against melanoma

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Frequently Asked Questions

Still have questions?