Reveal Unique Biological Insights
Single-cell spatial transcriptomics with the CosMx Spatial Molecular Imager (SMI) enables you to run high-plex transcriptomic analyses at single-cell and subcellular levels. Quantify and visualize thousands of RNA targets to drive deeper insights for cell atlas mapping, tissue phenotyping, cell-cell interactions, cellular processes, and biomarker discovery. Select one of these ultra-high plex panels covering a broad application area for your next study.
With over 18,000 targets, the CosMx Human Whole Transcriptome Panel gives researchers the ability to analyze the entire transcriptome in a single sample with cellular and subcellular spatial resolution. This panel provides a mechanism for unbiased differential gene expression analysis and biomarker discovery at the highest level.
The CosMx Universal Cell Characterization panel is designed to provide robust cell typing, cell-cell interaction analysis, and tissue mapping. Profile the expression of 1000 genes in a wide range of tissue types and solid tumors.
The Mouse Neuroscience panel is designed to provide robust cell typing, cell-cell interaction analysis and tissue profiling in mouse brain and other neuronal tissues. Profile the expression of 1000+ targets at subcellular resolution for the study of neuropathology targets covering AML, Huntington’s, Parkinson’s and neurodegeneration.
Spatially analyze the reactome at the single-cell level with the Human 6k Discovery panel. This panel is for defining ligand-receptor interactome, characterizing tissue microenvironment phenotypes, or developing a single-cell atlas. With over 6000 gene targets, profile the most significant genes across every biological pathway.
Profile the expression of 100+ transcripts covering immune cells and aspects of tumor biology relevant to IO therapies with the Human Immuno-oncology panel. A powerful tool for IO research, this assay provides robust cell typing and pathway analysis specific to IO targets, enabling deeper insights for therapeutic development.
Single-Cell Spatial Proteomics with CellScape
The CosMx SMI transcriptomic portfolio provides ultra-high plex analysis of transcripts in fresh frozen or FFPE tissue. To explore the biological implications of the transcriptomic differences and to validate these data, use our CellScape™ Precise Spatial Proteomics service. Our exclusive technology allows researchers to leverage quantitative spatial proteomic multiplexing to confirm gene expression changes as they translate into proteomic alterations.
How Our Service Works
Send Us Your Samples
The CosMx SMI platform is suitable for FFPE tissue and fresh frozen tissue. Send us your slides or blocks and we will process them for you.
We Do the Work
After we receive your samples, we get right to work with the CosMx SMI workflow.
We Deliver Your Data
Our scientists share your data with you and equip you with the tools for in-depth analysis, providing guidance on the best approach.
Featured Resources
Frequently Asked Questions
We specialize in spatial transcriptomics panels for CosMx, offering all the CosMx RNA panels in the Bruker Spatial Biology catalog. We can run protein panels if requested.
Our scientists share the data with you and assist you in the best approach to analysis. You know your project better than we do, so we equip you with the tools for in-depth analysis.
The primary sample type for CosMx is formalin-fixed paraffin-embedded (FFPE) tissue. We also run fresh frozen (FF) tissue. We can embed tissue onto slides as needed.