CosMx SMI Assays
Explore a broad portfolio of targeted and whole-transcriptome scale RNA and protein assays.
Assays Designed for Your Research
Explore the CosMx® Spatial Molecular Imager (SMI) portfolio of RNA and protein assays for high-plex spatial imaging at single-cell and subcellular resolution across human and mouse tissues. From targeted cell typing to whole-transcriptome discovery with proteomics, CosMx SMI Assays enable researchers to uncover cellular states, cell-to-cell interactions, and pathway biology directly in intact tissue.
CosMx SMI RNA Assays
CosMx SMI Protein Assays
CosMx Same-Cell Multiomics Workflow
Panel Comparison Table
| Assays | CosMx Whole Transcriptome Assay | CosMx Human 6K Discovery Assay | CosMx Universal Cell Characterization RNA Panel |
| Panel sizes | > 18,000 RNA targets in Human >21,000 RNA targets in Mouse | > 6,000 RNA targets | 1,000 RNA targets |
| Species | Human and Mouse | Human | Human and Mouse |
| Sample compatibility | FFPE, FF, organoids, cultured cells | FFPE, FF, organoids, cultured cells | FFPE, FF, organoids, cultured cells |
| Research Objective | Complete, Unbiased Spatial Exploration & Discovery | Reactome Cell State & Pathway Exploration | Targeted Gene Expression & Cell Typing |
| Custom Add-on Targets | Up to 200 targets | Up to 200 targets | Up to 50 targets |
Ready to see what CosMx SMI can do for your research?
Speak with a spatial biology specialist, request a quote, or explore open spatial biology datasets to accelerate your next discovery.