Bruker Spatial Biology Blog
Oncology
Q&A with Drs. Torsten Nielsen and Tony Ng and Angela Goytain: Development of a Sarcoma Gene Fusion Assay Faster Than FISH and Simpler than NGS
The NanoString nCounter is Research Use Only and not for diagnostic use. The views expressed herein are solely those of the interviewed researchers. Torsten Nielsen, MD, PhD is a pathologist…
Neuroscience
Q&A with Dr. Gregory Carter: Developing Computational Strategies and the MODEL-AD Consortium
Gregory Carter, Ph.D., is an Associate Professor at The Jackson Laboratory. His work is focused on developing computational strategies using genetic data to understand complex genetic systems. We recently spoke…
Neuroscience
Meta-analysis of AMP-AD Datasets Defines the Transcriptional Landscape of Alzheimer’s Disease
The Accelerating Medicines Partnership - Alzheimer’s Disease (AMP-AD) Consortium was formed to accelerate the development of diagnostics and therapeutics for this devastating and complex disease. One roadblock to development is…
Miscellaneous
NanoString-based publications 2018: A year in review
2018 was an incredibly productive year for scientific publications showcasing the NanoString platform and assays. We added nearly 500 publications of various scientific disciplines which are available on our website here.…
Oncology
Q&A with Dr. Juliane Nguyen: Exosome Profiling with miRNA and Biotech’s Next Breakthrough
Dr. Juliane Nguyen is a professor in the Department of Pharmaceutical Sciences at the University of Buffalo. Her Therapeutic Biomaterials Laboratory investigates using exosomes and other nanoscale carriers for the…
nCounter
The Votes Are In- What Causes qPCR and RNA-Seq Variability?
Retraction. A word feared by every scientist conducting lab experiments and publishing data. I came across an interesting article recently entitled “Sources of error in the retracted scientific literature” (Arturo…
Autoimmunity
Q&A with Darragh Duffy, Ph.D. – Understanding the Healthy Human Immune Response with the LabEx Milieu Interieur Project
Darragh Duffy, Ph.D., is the Scientific Manager of the LabEx Milieu Interieur project at the Institut Pasteur in Paris, France. This ambitious program started in 2011 with the mission to understand…
Digital Spatial Profiling Neuroscience
Q&A with Dr. Stefan Prokop – Alzheimer’s: From the Amyloid Hypothesis to the Cellular Phase and Beyond
Stefan Prokop, MD, is a Neuropathologist and Research Fellow at the University of Pennsylvania School of Medicine. His work is focused on Alzheimer’s Disease (AD) with a specific interest in…
nCounter
nCounter® PlexSet™ Reagents Let You Work Smarter, Not Harder
There are several options available to researchers looking to quantify and analyze gene expression. Most of those are time-consuming and highly technical processes that require extensive replicates and quality controls.…
Neuroscience
Researcher Profiles: How NanoString® Neuroscience Grant Program Winners are Utilizing nCounter® Technology
Earlier this year, five neuro grant program applicants were awarded nCounter® Neuropathology or Neuroinflammation Panels to profile 24 samples. Applications spanned a wide range of disease specific applications with the…
Digital Spatial Profiling
Q&A with Dr. Nick Reder: New Frontiers in Pathology with Digital Spatial Profiling and Light Sheet Microscopy
Dr. Nick Reder, MD, MPH, currently works at the Department of Pathology at the University of Washington in Seattle. Part of his time is spent in collaboration with mechanical engineers…
Digital Spatial Profiling
Revolutionizing Tissue Analysis with Digital Spatial Profiling
Recently, one of the early adopters of the Digital Spatial Profiling (DSP) technology, Michael Davies, MD, PhD, the Deputy Chairman and Associate Professor in the Department of Melanoma Medical Oncology…