Resource Type: Blog

The ability to simultaneously map morphology, RNA, and protein at the subcellular level is the new frontier in cell biology. While the CosMx^® Spatial Molecular Imager (SMI) is renowned for…

With AGBT 2025 right around the corner and exciting announcements from Bruker Spatial Biology coming, we’re here to bring you the latest updates, innovations, and resources in spatial biology. Upcoming…

As spatial biology reshapes the future of biomedical research, spatial transcriptomics has emerged as one of the most powerful tools for revealing complex tissue biology. Technologies like the CosMx^® Spatial…

Tips to optimize the CosMx Multiomics sample prep for fragile tissues The CosMx multiomics platform enables sequential protein and RNA analysis on the same tissue sample, combining a 64-plex protein…

This month brings exciting milestones across our portfolio. Washington University School of Medicine’s Orr Lab has been named a Bruker Spatial Biology Center of Excellence, marking a new chapter in…

Explore the CosMx SMI 2.0: Higher RNA sensitivity, whole transcriptome imaging, and faster high fidelity, subcellular spatial transcriptomics.

We're excited to share a major step forward: the nCounter^® platform is now enabling simplified RNA and protein analysis in a single workflow. Dive into our newest capabilities for bulk multiomics,…

Over the last few years, more and more researchers have embraced multiplex immunofluorescence (mIF), and for good reason. The ability to visualize many biomarkers in a single tissue section can…

This year’s American Association for Cancer Research (AACR) Annual Meeting highlighted the power of spatial and multiomics technologies to illuminate the cellular and molecular complexity of cancer. Across all five…

The CosMx^® Spatial Molecular Imager (SMI) instrument performs fluorescent imaging to read out in-situ hybridized fluorescent reporters which uniquely identify RNA transcripts. The presence of tissue autofluorescence background may reduce…

Compare CosMx SMI versus scRNA-seq and see how spatial transcriptomics reveals more biology in intact tissue and with subcellular resolution.