October 2025 Newsletter

This month brings exciting milestones across our portfolio. Washington University School of Medicine’s Orr Lab has been named a Bruker Spatial Biology Center of Excellence, marking a new chapter in collaborative research on aging and neurodegeneration. We are also introducing the GeoMx® Discovery Proteome Atlas, the highest plex antibody-based spatial proteomics assay, and opening pre-orders for CosMx® Multiomics, enabling same-cell RNA and protein detection.
Don’t miss our upcoming Multiomics Summit and an AMA (Ask Me Anything) with Dr. Joe Beechem, plus new resources like the CellScape™ PSP Knowledge Base. And if you are joining the Galaxy Tour this fall, we will see you on the road!
What's New
Orr Lab Named Bruker Spatial Biology Center of Excellence
The Orr Lab at Washington University School of Medicine has been named a Bruker Spatial Biology Center of Excellence. Led by Dr. Miranda Orr, the lab will serve as a pilot site for combining Bruker’s spatial transcriptomics and proteomics platforms to generate rich datasets that advance our understanding of aging and neurodegeneration, particularly Alzheimer’s disease.
Introducing GeoMx Discovery Proteome Atlas
Our new GeoMx Discovery Proteome Atlas (DPA) is the highest-plex antibody-based spatial proteomics assay, measuring 1200+ proteins across key human pathways.
Built for unprecedented discovery on the GeoMx Digital Spatial Profiler, DPA lets you identify new biomarker and drug target candidates faster than ever, all within your existing GeoMx DSP workflow.
Order CosMx Multiomics Today
Unlimited spatial exploration requires high-fidelity data. With the launch of CosMx Multiomics, researchers can now interrogate both RNA and protein in and around the same cell, enabling a deeper understanding of cellular function and context.
The CosMx Spatial Molecular Imager (SMI) same-cell multiomic workflow is the only solution to enable simultaneous detection of over 19,000 RNA targets and 76 proteins within the same FFPE tissue section, with single-cell resolution. This high-fidelity spatial transcriptomics platform allows scientists to move from inferring to direct biological insights.
Save the Date: Multiomics Unleashed and The Future of Integrative Biology
Join us for an exciting presentation of discovery. Dr. Joseph Beechem and Dr. Oliver Braubach will share the latest innovations across Bruker's expanding portfolio of spatial biology solutions. From transcriptomics to proteomics, this summit will showcase how multiomic technologies are driving deeper insights into cellular function and disease.
Summit Highlights:
- nCounter® Multiomics Solutions
- GeoMx Discovery Proteome Atlas (DPA)
- CosMx Same-cell Multiomics
- Recent advances in Cellscape™ Precise Spatial Proteomics
Plus… an introduction to the Beacon optofluidic single-cell technology. In addition, we will feature special presentations from leading scientists who are pushing the boundaries of biology in oncology, immunology, and neuroscience.
Thursday October 16, 11 am EDT / 8 am PDT
Resource Spotlight
Ask Me Anything (AMA) with Dr. Joseph Beechem
In partnership with Technology Networks, Dr. Joseph Beechem, our Chief Scientific Officer and pioneer in spatial biology innovation, hosted an open conversation on the transformative capabilities of the CosMx Spatial Molecular Imager and the GeoMx Digital Spatial Profiler for spatial multiomics. Whether mapping cell-to-cell interactions with the whole transcriptome or profiling thousands of protein targets, this AMA covered questions spanning spatial transcriptomics, multiomics, and single-cell analysis. Watch the replay to gain clarity and discover what’s new in spatial biology.
Introducing the CellScape Precise Spatial Proteomics Knowledge Base
The CellScape Precise Spatial Proteomics (PSP) Knowledge Base is now live! The Knowledge Base is a comprehensive technical hub designed to support your research journey. Organized by commonly asked questions, you can now access detailed guides, troubleshooting tips, and best practices to optimize your use of the CellScape PSP platform.
Whether you're new to spatial proteomics or looking to deepen your expertise, this resource is built to help you achieve more, with confidence.
ICYMI (In Case You Missed It)
nCounter Multiomics: Learn More
On-demand viewing is available for our webinar, nCounter 201: Bulk Multiomics Made Simple. Learn how you can measure RNA and protein together from the same FFPE or FF sample using a simple 3-step workflow. The nCounter platform offers simplicity, precision and speed for analyzing both protein and RNA from the same sample.
Webinar Highlights:
- Fit-for-purpose targeted gene expression analysis applications
- Benefits of adding a multiomics approach to your research
- nCounter Analysis System advantages for bulk multiomics research
- Overview of the nCounter bulk multiomics workflow
- Panel content supported with nCounter multiomics
- Multiomics data analysis highlights
The Journey Continues
Our fall session of the Galaxy Spatial Tour is taking off! Check out the list of stops from Europe (Leuven, Stockholm, Cambridge & Milan) through North America (Chicago, Boston, Philadelphia & Atlanta). Attendees will gain insights into emerging discoveries made by pioneering users and powered by single-cell whole transcriptomics and discovery-based multiomics platforms.
A special thank you goes out to everyone who joined us during the first half of the year and we look forward to hitting the road again!
High-Fidelity Spatial Transcriptomics: Understanding Subcellular Spatial Molecular Imaging
Watch our webinar on-demand to explore how whole transcriptome subcellular molecular imaging is reshaping the future of spatial biology. Featuring three leading voices in the field of spatial transcriptomics who use the technology to uncover cellular mechanisms, therapeutic responses and multimodal insights:
- Arutha Kulasinghe, PhD, research fellow at the University of Queensland, presents his work on spatial single-cell dissection of immunotherapy responses.
- Daniel Bear, PhD, vice president of AI research at Noetik, discusses interrogating patient-scale biology with multimodal spatial foundation models.
- Nigel Jamieson, PhD, clinical senior lecturer and consultant HPB surgeon at Cancer Research UK and clinician scientist at the University of Glasgow, gives a special presentation titled ‘From Bedside to Bench: Spatial Omics Across a Spectrum of Human Disease.’
At Bruker Spatial Biology, we are dedicated to advancing science through innovation, collaboration, and unmatched flexibility. Follow along for more updates, resources, and opportunities to transform your research.