Bruker Spatial Biology Blog
Canopy Biosciences
Research Spotlight: Mara De Martino Leveraging the CellScape platform and MALDI for Glioblastoma Research
In a recent presentation, Mara De Martino, PhD, a postdoc in Dr. Claire Vanpouille-Box's lab in the Weill Cornell Medicine radiation oncology department, shared her research on radiotherapy-treated glioblastoma, leveraging…
CosMx SMI
Tips when performing CosMx® data analysis with AtoMx SIP
Single-cell spatial biology opens doors to unprecedented scientific questions requiring the development of new computational workflows and approaches to analyze and interpret data. Whether you are new to single-cell spatial…
Miscellaneous
Photobleaching as a Signal Removal Tool in Multiplex Fluorescence Imaging
In fluorescence microscopy, fluorophores absorb light at specific wavelengths. This absorption leads to the excitation of the fluorophore’s electrons. When the electrons return to the ground state, it dissipates that…
Immunology Oncology
Data-driven Assay Expansion: Re-examine Multiplex Immunofluorescence Slides Based on Initial Staining Results
Imagine this: you’ve just completed your multiplex immunofluorescence experiment, and when examining your images, you notice something intriguing or novel about the tissue or a certain subset of cells. In…
Canopy Biosciences
Will Leineweber and the Emma Lundberg Lab: Pairing CellScape with live cell imaging to explore cancer cell migration
Will Leineweber, a postdoc in Emma Lundberg's lab at Stanford University, recently spoke at the Annual Meeting of the American Society for Cancer Research (AACR2024) about his research exploring heterogenous…
Spatial Biology
Spatial Biology Just Got Bigger
Introducing CellScape® Whole-Slide Imaging Chamber Now you can convert any standard microscope slide into a microfluidic chamber for automated multiplex staining, high-resolution imaging, and safe sample archiving. Read more about…
CosMx SMI
Tips when Generating Single-Cell Spatial Data: Post Run H&E and Antibody Staining
We are excited to share the third installment of tips for successful CosMx® SMI single-cell spatial runs at 1000-plex. Our first installment of tips focused on data by tissue and…
CosMx SMI
Tips When Generating Single-Cell Spatial Data: Sample Selection
We are excited to share the second installment of tips for successful CosMx® SMI single-cell spatial runs at 1000-plex. Our first installment of tips focused on data by tissue and…
Canopy Biosciences
Highly Multiplexed Deep Cell Phenotyping with ChipCytometry™
Immune cell phenotyping is an important capability for immunology and immuno-oncology research, clinical trials, and therapeutic monitoring. More specifically, immune phenotyping applications include: Understanding immune responses to pathogens (viruses, bacteria,…
Canopy Biosciences Spatial Biology
Spatial Biology: What it is, why it matters, and how to access it
This article will explore the general topic of spatial biology, providing you with an overview of the field, describing why it is an important area of emerging research, and sharing…
Canopy Biosciences
Software Options Available for Spatial Analysis
Advanced data analysis for spatial biology : What are the best options available? CellScape® and Enable Medicine: What is Enable Medicine? In the dynamic landscape of medical research, the fusion of…
Canopy Biosciences
High Dynamic Range Microscopy in Immunofluorescence Imaging
Learn about High Dynamic Range (HDR) microscopy—what it is and why it will add value to your immunofluorescence imaging. High dynamic range in the fall Autumn is a beautiful time…