Bruker Spatial Biology Blog

Immunology Oncology

Data-driven Assay Expansion: Re-examine Multiplex Immunofluorescence Slides Based on Initial Staining Results

Imagine this: you’ve just completed your multiplex immunofluorescence experiment, and when examining your images, you notice something intriguing or novel about the tissue or a certain subset of cells. In…
Bruker Spatial Biology / July 25, 2024

Canopy Biosciences

Will Leineweber and the Emma Lundberg Lab: Pairing CellScape with live cell imaging to explore cancer cell migration

Will Leineweber, a postdoc in Emma Lundberg's lab at Stanford University, recently spoke at the Annual Meeting of the American Society for Cancer Research (AACR2024) about his research exploring heterogenous…
Bruker Spatial Biology / June 28, 2024

Spatial Biology

Spatial Biology Just Got Bigger

Introducing CellScape™ Whole-Slide Imaging Chamber Now you can convert any standard microscope slide into a microfluidic chamber for automated multiplex staining, high-resolution imaging, and safe sample archiving. Read more about…
Bruker Spatial Biology / May 18, 2024
CosMx tissue image

CosMx SMI

Tips when Generating Single-Cell Spatial Data: Post Run H&E and Antibody Staining

We are excited to share the third installment of tips for successful CosMx® SMI single-cell spatial runs at 1000-plex. Our first installment of tips focused on data by tissue and…
NanoString / May 9, 2024
CosMx tissue image

CosMx SMI

Tips When Generating Single-Cell Spatial Data: Sample Selection 

We are excited to share the second installment of tips for successful CosMx® SMI single-cell spatial runs at 1000-plex. Our first installment of tips focused on data by tissue and…
NanoString / February 13, 2024

Canopy Biosciences

Highly Multiplexed Deep Cell Phenotyping with ChipCytometry™

Immune cell phenotyping is an important capability for immunology and immuno-oncology research, clinical trials, and therapeutic monitoring. More specifically, immune phenotyping applications include: Understanding immune responses to pathogens (viruses, bacteria,…
Bruker Spatial Biology / February 6, 2024

Canopy Biosciences Spatial Biology

Spatial Biology: What it is, why it matters, and how to access it

This article will explore the general topic of spatial biology, providing you with an overview of the field, describing why it is an important area of emerging research, and sharing…
Bruker Spatial Biology / February 6, 2024

Canopy Biosciences

Software Options Available for Spatial Analysis

Advanced data analysis for spatial biology : What are the best options available? CellScape™ and Enable Medicine: What is Enable Medicine? In the dynamic landscape of medical research, the fusion of…
Bruker Spatial Biology / February 6, 2024
Autumn in St. Louis, captured in HDR. Colorful trees in Forest Park (St. Louis, Missouri) were captured using multiple different exposure times.

Canopy Biosciences

High Dynamic Range Microscopy in Immunofluorescence Imaging

Learn about High Dynamic Range (HDR) microscopy—what it is and why it will add value to your immunofluorescence imaging. High dynamic range in the fall Autumn is a beautiful time…
Bruker Spatial Biology / February 5, 2024

Spatial Biology

NanoString Powered by NVIDIA GPU Technology Accelerates Scientific Discovery and the Age of Spatial Biology

For researchers studying diseases that cruelly take the lives of millions — Alzheimer’s disease, lung, colon, breast, and pancreatic cancer, among others — it has been a long-held dream to…
Sriya Malladi and Meg O'Conor / January 9, 2024
CosMx tissue image

CosMx SMI

Top 3 Tips for Successful CosMx® SMI Single-cell Spatial Runs at 1000 plex

We are excited to share insights and recommendations to enhance your experience with CosMx® SMI 1000-plex RNA assays. The quality of single-cell spatial data is influenced by various factors, and…
NanoString / December 13, 2023
Geo location

GeoMx DSP

Getting Started with Your First GeoMx® DSP Experiment: A Step-by-Step Guide

The GeoMx Digital Spatial Profiler (DSP) is a powerful tool for spatial multiomics, the in situ analysis of RNA and protein expression in tissue sections. GeoMx DSP gives you the…
Elizabeth Schneider / December 11, 2023