Bruker Spatial Biology Blog
Spatial Biology
NanoString Powered by NVIDIA GPU Technology Accelerates Scientific Discovery and the Age of Spatial Biology
For researchers studying diseases that cruelly take the lives of millions — Alzheimer’s disease, lung, colon, breast, and pancreatic cancer, among others — it has been a long-held dream to…
CosMx SMI
Top 3 Tips for Successful CosMx® SMI Single-cell Spatial Runs at 1000 plex
We are excited to share insights and recommendations to enhance your experience with CosMx® SMI 1000-plex RNA assays. The quality of single-cell spatial data is influenced by various factors, and…
GeoMx DSP
Getting Started with Your First GeoMx® DSP Experiment: A Step-by-Step Guide
The GeoMx Digital Spatial Profiler (DSP) is a powerful tool for spatial multiomics, the in situ analysis of RNA and protein expression in tissue sections. GeoMx DSP gives you the…
nCounter Oncology
GEP Signatures Unleashed: The LST for Diffused Large B-Cell Lymphoma, DLBCL, Subtyping and Its Expanding Applications
Gene expression profiling (GEP) signatures, comprising sets of genes characteristic of specific diseases, tissues, cell types, cell states, or biological perturbation, hold significant diagnostic, predictive, and prognostic value, positioning them…
CosMx SMI Spatial Biology
Complex Cell Segmentation and Its Significance in Spatial Biology
In research, scientists are continually pushing boundaries to gain deeper insights into biology, medicine, and drug discovery. Single-cell spatial imaging has emerged as a powerful technology in the field of…
Immunology nCounter Oncology
TIS GEP: Use Cases in Sample Stratification, Assessment of Treatment Effect, and as a Component of a Multivariate Biomarker
Introduction to the TIS Gene Expression Profile Innovations in multiplex gene expression analysis are revolutionizing translational research and clinical practices by enabling identification of gene signatures involved in various biological…
Multiomics Spatial Analysis Spatial Biology Spatial Transcriptomics
GeoMx® DSP Spatial Proteogenomics datasets now available on Illumina® BaseSpace™ Sequence Hub
NanoString and Illumina have collaborated to release two new demo datasets of GeoMx Digital Spatial Profiler (DSP) data on the Illumina BaseSpace Sequence Hub (BSSH) cloud. Spatial proteogenomics enables new…
Oncology
Utility of PAM50 GEP Signature as a Biomarker for Exploratory Endpoints in Drug Discovery and Development
The Need for Gene Expression Profiling Gene expression profiling has emerged as a genomic tool that can help decipher the complexity of cancer subtyping. Conceptually, cancer is a fairly simple…
Canopy Biosciences
Why You Need to Increase the Throughput of Your Single-Cell Imaging Experiments
Is your world filled with terms like spatial biology, single-cell analysis, and multiplexed imaging? With a variety of single-cell imaging techniques on the market, it can be time consuming to…
Canopy Biosciences
Developing new protocols to expand the utility of ChipCytometry™
Researcher Spotlight Developing new protocols to expand the utility of ChipCytometry Featuring Sebastian Jarosch, MScInstitute for Medical Microbiology, Immunology, and Hygiene, Technical University of Munich "We have developed a series…
Canopy Biosciences
Profiling the Tumor Microenvironment of Neuroblastoma Using ChipCytometry™
Researcher Spotlight Profiling the Tumor Microenvironment of Neuroblastoma Using ChipCytometry™ Featuring Margarida Neves, MSc, PhD Student, Department of Pathology, UCL Cancer Institute, University College London Department of Translational Medicine, Autolus…
Spatial Biology
Why is the human proteome important?
The Human Protein Atlas is one of the world’s largest biological databases, containing spatial expression profiles for all known proteins expressed in human organs and tissues. It contains a vast…