Your Spatial Biology Success Story Starts Here
Researchers use spatial biology to understand how biological processes occur within the context of their physical surroundings. Spatial biology adds a vital, contextual layer to our existing understanding of cell biology.
In Situ Analysis
Reduce the risk of lost cellular information and gain novel insights by analyzing your cells in their original spatial context.
High-Content Data
Quantify hundreds to thousands of transcripts or proteins simultaneously with the additional layer of spatial architecture information.
Large Scale Scanning
See the whole picture with unbiased transcriptomic or high-plex proteomic analysis. Pair them together for complementary exploration.
Understand the TME
Identify how cells and molecules are spatially organized within tissue and tumor microenvironments to understand disease progression.
Structure / Function
Utilize cell location, surroundings, and structures to define phenotypes, states, and ultimately cell and tissue function.
Precision Medicine
Identify patterns between transcripts, proteins, and cell types to develop more effective and precise personalized treatments.
Frequently Asked Questions
Spatial biology is the study of cells and molecules in their histological context. Using spatial biology techniques, you can see which genes and proteins are expressed, where they are expressed, and investigate interactions between relevant cells and molecules.
Spatial profiling, or spatial gene expression, combines the detection of expression of thousands of genes or entire genomes with their spatial location within a cell. Regions of interest can be visualized, and corresponding transcripts can be collected for sequencing through a technique called spatial sequencing.
Spatial phenotyping combines single-cell fluorescent microscopy and high-plex protein biomarker detection. Single cells are detected in their spatial context, and their phenotype is characterized via the multiplex detection of biomarker expression. Information about each cell, its phenotypic profile, and its location, are collected and can be compared against other cells or regions of interest across the entire tissue.